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What Are The Small Cells and Non-Small Cell Lung Cancer Differences?
28.11.2018 1 288 0 Admin

What Are The Small Cells and Non-Small Cell Lung Cancer Differences?

Treatment methods

There are two main types of lung cancers: small cell and non small cell lung cancer. Although both cancers affect the lungs, they have several important differences, including the way they are treated and the course of the disease.

When the small cell lung cancer cells are examined under a microscope, the cancer cells are really small and have a round appearance. Non-small cell lung cancer cells are bigger in size.

About 15% of all lung cancers are of small cell structure.

There are 4 main subtypes of non-small cell lung cancer. These are adenocarcinoma, squamous (flat) cell and large cell carcinoma, and do not enter any class.

Is there a difference in symptoms?

Both small and NSCLCcause similar symptoms. More than half of patients with lung cancer do not have any complaints until the cancer is advanced. Therefore, it is important for people at high risk to have lung cancer screening because they are both aware of possible symptoms and intense smoking.

The following symptoms may indicate lung cancer:
• loss of appetite
• bloody sputum
• chest pain
• long lasting cough
• difficulty in swallowing
• feeling permanently sluggish, with no apparent justification
• shortness of breath
• especially face and neck swelling
• wheezing

The symptoms of small cell and non-small cell lung cancer (NSCLC) are largely similar. However, small cell lung cancer usually spreads faster because they can cause more fatigue and weight loss. Lung cancer can lead to bone pain due to bone metastases in later stages.
Is there a difference in reasons?

Smoking is arguably the most important risk factor for non-small cell lung cancer. Smoke and chemicals in it cause carcinogens, damage to the lungs and cause cell changes that can cause cancer. Even before the worldwide spread of smoking, lung cancer was one of the rare cancers.
However, while 99% of small cell lung cancers are caused by smoking, the role of smoking in non-small cell lung cancers is around 90%.

Other causes of NSCLC include:
• Exposure to second or even third-hand tobacco smoke
• Family history of lung cancer
• Having HIV
• Exposure to environmental radon

Is there a difference in diagnosis?

The location of the tumor gives us a clue about the type of cancer, but it is unclear what kind of lung cancer a person carries until a pathologist finds and identifies cancer cells in the microscope.

The pathologist can then examine the size and appearance of the cell to determine whether the cancer is small-cell or small-celled.


The test samples used to diagnose both types of lung cancer include:
The diagnosis of lung cancer is usually made by a biopsy performed after a computed tomography or PET-CT scan taken in suspected patients.

Biopsy: Biopsy involves testing a small sample of potentially cancerous cells in the lungs. Tomography-guided lung biopsy is the most preferred method for sampling from tumors in lungs. Tomography biopsy results in less side effects and allows for more effective biopsy.

Bronchoscopy: A special device called a bronchoscope, which eventually has a camera, is inserted into the mouth or nose. This method is used by a pediatrician or thoracic surgeon to look into the lungs and take tissue samples.
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